Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Reexamination Certificate
2006-12-12
2006-12-12
Jones, Dameron L. (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
C424S001110, C424S001690, C424S001650, C534S007000, C514S014800, C514S015800, C514S016700
Reexamination Certificate
active
07147838
ABSTRACT:
A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
REFERENCES:
patent: 6200546 (2001-03-01), Hoffman et al.
patent: 6921526 (2005-07-01), Hoffman et al.
Higginbotham Chrys-Ann
Hoffman Timothy J.
Li Ning
Sieckman Gary
Volkert Wynn A.
Curators of the University of Missouri
Jones Dameron L.
Kohn Kenneth I.
Kohn & Associates PLLC
LandOfFree
Gastrin receptor-avid peptide conjugates does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Gastrin receptor-avid peptide conjugates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gastrin receptor-avid peptide conjugates will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3720122