Heat sensitive bacterial alkaline phosphatase

Details Heat sensitive bacterial alkaline phosphatase Heat sensitive bacterial alkaline phosphatase

1983-10-19

1988-01-19

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 21, 435 6, C12N 916, C12Q 142, C12Q 168

Patent

active

047204583

ABSTRACT:
This invention discloses a newly discovered enzyme and a method of producing said enzyme wherein said enzyme is completely inactivated by treatment with temperatures of 50.degree. or higher for 10 minutes or longer. The alkaline phosphatase is isolated from the psychrophilic bacteria, particularly bacteria from certain areas of the oceans surrounding Antarctica. The preferred alkaline phosphatase is derived from the bacteria HK-47 (ATCC 39469).

REFERENCES:
Glen et al, Journal of Biological Chemistry, vol. 246, pp. 1556-1565 (1974).
Advances in Enzymology, vol. 55, pp. 381-386 (1983).

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