Fluorescent tags for amino acid and nucleic acid analysis

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007100, C435S007200, C536S023100, C536S024300, C536S026600, C530S300000, C530S350000

Reexamination Certificate

active

07150967

ABSTRACT:
Methods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluorescent reactions products of the mercurimethyl-dihydropsoralen compounds or derivatives thereof attached to a thiol containing species and nucleic acids fluorescently labeled with these reaction products are also provided.

REFERENCES:
patent: 4279992 (1981-07-01), Boguslaski et al.
patent: 4956480 (1990-09-01), Robinson
patent: 5188934 (1993-02-01), Menchen et al.
patent: 5248782 (1993-09-01), Haugland et al.
patent: 5268486 (1993-12-01), Waggoner et al.
patent: 5274113 (1993-12-01), Kang et al.
patent: 5371241 (1994-12-01), Brush
patent: 5433896 (1995-07-01), Kang et al.
patent: 5437980 (1995-08-01), Haugland
patent: 5442045 (1995-08-01), Haugland et al.
patent: 5451663 (1995-09-01), Kang et al.
patent: 5583236 (1996-12-01), Brush
patent: 5627027 (1997-05-01), Waggoner
patent: 5654442 (1997-08-01), Menchen et al.
patent: 5658735 (1997-08-01), Lee
patent: 5696157 (1997-12-01), Wang et al.
patent: 5700921 (1997-12-01), Westling et al.
patent: 6255324 (2001-07-01), Heindel et al.
patent: 6291203 (2001-09-01), Poot et al.
patent: 6299055 (2001-10-01), Pitel
patent: 6335446 (2002-01-01), Pennington et al.
Saffran et al. “Site-directed psoralen crosslinking of DNA” Proc. Natl. Acad. Sci. USA, vol. 79, pp. 4594-4598, 1982.
Naveenan et al. “Reactive Thiol Grooups in Rat Liver Acid Phosphatase” Enzyme 33, pp. 197-204 1985.
Song et al., “Labeling of Nucleic Acids with Psoralens”, Annals New York Acad. Sci. 1980 346:355-367.
Chapter 2 of the commerical catalog for Molecular Probes, Inc. Richard Haugland, Handbook of Fluorescent Probes and Research Chemicals, 6th Edition 1996.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Fluorescent tags for amino acid and nucleic acid analysis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fluorescent tags for amino acid and nucleic acid analysis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent tags for amino acid and nucleic acid analysis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3715391

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.