Methods of analysis of allelic imbalance

Details Methods of analysis of allelic imbalance Methods of analysis of allelic imbalance

2006-08-29

2006-08-29

Goldberg, Jeanine A. (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091100, C435S091200, C435S287100, C435S287200, C536S023100, C536S024300

Reexamination Certificate

active

07097976

ABSTRACT:
Methods are provided for identification of genes that are imprinted. In another embodiment methods are provided for identification and analysis of genes whose expression shows allelic imbalance. The expression products transcribed from genes that are present in the genome as two or more alleles may be distinguished by hybridization to an array designed to interrogate individual alleles. Genes whose transcription products are present in amounts that vary from expected are candidates for allelic imbalance, imprinting and imprinting errors.

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Lee M.P. Genome-wide search of imprinted genes. http://lpg.nci.nih.gov/LPG/lee/proj2.

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