Process monitoring and particle characterization with...

Details Process monitoring and particle characterization with... Process monitoring and particle characterization with...

2006-10-03

2006-10-03

Larkin, Daniel S. (Department: 2856)

Measuring and testing

Liquid analysis or analysis of the suspension of solids in a...

Content or effect of a constituent of a liquid mixture

C073S064530, C073S590000, C073S596000, C073S597000, C073S599000

Reexamination Certificate

active

07114375

ABSTRACT:
A fermention process is monitored by detecting ultrasound backscattered from the cells as a function of time. A transducer46is placed in a fermentor30and transmits ultrasound towards a reflecting surface50. The transducer receives that portion of the ultrasound which reflects from the reflecting surface50, as well as that portion of the ultrasound which backscatters from cells34between the transducer46and the reflecting surface50. Signals from the transducer are conditioned and subsequently processed to provide output to a controller regarding the status of the fermentation process in real time. The backscattering measurements can be used to determine a growth phase transition, such as the transition between the logarithmic growth phase of the cells and their stationary phase.

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