Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2006-08-15
2006-08-15
Lilling, Herbert J. (Department: 1651)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S255100
Reexamination Certificate
active
07091016
ABSTRACT:
Carbonyl reductase (CR) of a yeast strain,Kluyveromyces marxianus, and its isolation and purification method thereof is provided. The reduction reaction by the reductase obtained in the present invention is more stereospecific and requires less cost and time than the reduction reactions by the microorganisms or by the reducing enzymes obtained from a chemical synthesis.
REFERENCES:
patent: 2003/0175886 (2003-09-01), Han et al.
patent: 0 290 385 (1988-11-01), None
Online Korean Catalogue 2003 No. 1930 p. 4 Strain 7155Kluyveromyces marxianus.
Wermuth, Bendicht, “Enzymology of Carbonyl Metabolism 2: Aldehyde Dehydrogenase, Aldo-Keto Reductase, and Alcohol Dehydrogenase”, Biol. Res., 1985, vol. 174, pp. 209-230.
Oppermann, Udo C.T., et al., “Molecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions”, Toxicology, 2000, vol. 144, pp. 71-81.
Cha Joo-Hwan
Han Ye-Sun
Kim Wook-Hyun
Koh Hun-Yeong
Lee Jong-Soo
Darby & Darby
Korea Institute of Science and Technology
Lilling Herbert J.
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