Process for synthesizing N-aryl piperazines with chiral...

Details Process for synthesizing N-aryl piperazines with chiral... Process for synthesizing N-aryl piperazines with chiral...

2006-08-15

2006-08-15

Bernhardt, Emily (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S364000

Reexamination Certificate

active

07091349

ABSTRACT:
A process for formation of N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane side-chains having the structure shown in formula below, and for making intermediate compounds therefor.In this process, chirality is introduced at the piperazine ring formation step and 2-aminopyridyl substitution is incorporated via displacement. The resulting N, N′ disubstituted piperazines act on the central nervous system at 5HT receptors.

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