Chemokine receptor obtained from a cDNA library of fetal...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S387100, C530S388220

Reexamination Certificate

active

07001731

ABSTRACT:
The invention provides novel polynucleotides isolated from cDNA libraries of human fetal liver-spleen and fetal liver as well as polypeptides encoded by these polynucleotides. The polypeptide is a human chemokine receptor that is a member of a family of G protein-coupled receptors characterized by seven transmembrane domains. Other aspects of the invention include vectors containing polynucleotides of the invention and related host cells as well a processes for producing chemokine receptor polypeptides, and antibodies specific for such polypeptides.

REFERENCES:
patent: 5440021 (1995-08-01), Chuntharapai et al.
patent: 5591618 (1997-01-01), Chantry et al.
patent: 5691188 (1997-11-01), Pausch et al.
patent: 5739029 (1998-04-01), King et al.
patent: 5744324 (1998-04-01), Lester et al.
patent: 5747267 (1998-05-01), Mulvihill et al.
patent: 5750370 (1998-05-01), Li et al.
patent: 0899332 (1999-03-01), None
patent: WO 94 12635 (1994-06-01), None
Doerks et al. Protein annotation: detective work for function prediction. Trends in Genetics. Jun. 1998, vol. 14, No. 6, pp. 248-250.
Brenner et al. Errors in Genome Annotation. Trends in Genetics 1999, 15:132-133.
Bork et al. Go Hunting in sequence database but watch out for the traps. Trends in Genetics 1996, 12:425-427.
Barritt et al., “An evaluation of strategies available for the identification of GTP-binding proteins required in intracellular signaling pathways” Cell. Signal. 9:207-218 No. 3/4 (1997).
Carmeci et al., “Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer” Genomics 45:607-617 (1997).
Chidiac “Rethinking receptor-G-protein-effector interactions” Biochemical Pharmacology 55:549-556 (1998).
Dohlman et al., “Model systems for the study of seven-transmembrane segment receptors” annu. Biochem 60:653-88 (1991).
Feng et al. “Cloning of a novel member of the G protein-coupled receptor family related to peptide receptors” Biochem Biophys Res Commun 231651-654 (1997).
Grady et al. “Turning off the signal: mechanisms that attenuate signaling by G protein-coupled receptors” Am J Physiol 273:G586-601 (1997).
Kvigedal et al. “A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue” FEBS Lett. 407:59-62 (1997).
Lefkowitz RJ “G-protein-coupled receptor kinases” Cell 74:409-412 (1993).
Milligan et al. “Biochemical approaches to examine the specificity of interactions between receptors and guanine nucleotide binding proteins” J of Receptors & Signal Transduction Research 15:253-265 (1995).
O'Dowd et al. Discovery of three novel G-protein-coupled receptor genes' Genomics 47:310-313 (1998).
Owman et al. “Cloning and characterization of human cDNA encoding a novel heptaheix receptor derived from B cells and expressed in Burkitts lymphoma” Biochem Biophys Res Commun 228:285-292 (1996).
Power et al. “Cloning and characterization of human chemokine receptors” Trends in Pharmacological Sciences, GB, Elsevier Trends Journal 17:209-213 (1996).
Probst et al “Seqeunce alignment of the G-protein coupled receptor superfamily” DNA and Cell Biology 11:1-20 (1992).
International Search Report In PCT/US99/12829.
Smith et al. “Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression” Science 277:959-964 (1997).
Simon et al., “Macrophage markers 25F9 and 27E10 on human keratinocytes in normal and diseased skin” J Dermatol 20:618-622 (1993).
Martinez-Pomarez et al., “Macrophage membrane molecules : markers of tissue differentiation and heterogeneity” Immunobiol 195:407-416 (1996).
Kodelja V and Goerdt S, “Dissection of macrophage differentiation pathways in cutaneous macrophage disorders and in vitro” Exp Dermatol 3:257-268 (1994).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chemokine receptor obtained from a cDNA library of fetal... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemokine receptor obtained from a cDNA library of fetal..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemokine receptor obtained from a cDNA library of fetal... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3705944

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.