5-aminoalkyl-pyrazolo[4,3-d]pyrimidines with a...

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

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Details

C544S262000, C514S262100, C514S253030, C514S252160

Reexamination Certificate

active

07060823

ABSTRACT:
The present invention relates to 5-aminomethylpyrazolo[4,3-d]pyrimidines of the general formula (I)in which the radicals R1to R6have the meaning indicated in the text. The compounds show phosphodiesterase V inhibition and can be employed for the treatment of conditions of the cardiovascular system and for the treatment of potency disorders.

REFERENCES:
patent: 5075310 (1991-12-01), Coates et al.
patent: 5436233 (1995-07-01), Lee et al.
patent: 6001830 (1999-12-01), Lee et al.
patent: 6100270 (2000-08-01), Campbell
patent: 6130223 (2000-10-01), Jonas et al.
patent: 6495554 (2002-12-01), Jonas et al.
patent: 6777419 (2004-08-01), Jonas et al.
patent: 0349239 (1990-01-01), None
patent: 0579496 (1994-01-01), None
patent: WO 9616657 (1996-06-01), None
patent: WO 9817668 (1998-04-01), None
patent: WO 9928325 (1999-06-01), None
patent: WO 0118004 (2001-03-01), None
Czarniecki, M., et al., “Inhibitors of Type I and V Phosphodiesterase: Elevation of cGMP as a Therapeutic Strategy,” Annu. Rep. Med. Chem., 1996, pp. 61-70, vol. 31, XP002180272, New York; p. 64, examples 11, 12, 13, 14; p. 66, example 20, 21, the whole document.
Dumaitre B et al., “Synthesis and Cyclic GMP Phosphodiestrase Inhibitory Activity of a Series of 6-Phenylpyrazolou3,4-Dpyrimidones,” Journal of Medical Chemistry, American Chemical Society, Washington, US, 1996, pp. 1635-1644, vol. 39, No. 8, XP000651134, ISSN: 0022-2623; p. 1683, tab. 1, No. 8, 10, 11, the whole document.

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