N-type calcium channel antagonists for the treatment of pain

Details N-type calcium channel antagonists for the treatment of pain N-type calcium channel antagonists for the treatment of pain

2006-12-26

2006-12-26

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S161000

Reexamination Certificate

active

07153865

ABSTRACT:
Compounds useful for the treatment of pain in accord with the following structural diagram,wherein A, R1, b, R3, d, R4, R5, R6and R7are any of a number of groups as defined in the specification, and pharmaceutical compositions and methods of treatment utilizing such compounds.

REFERENCES:
patent: 4357333 (1982-11-01), Archibald et al.
patent: WO 0064877 (2000-11-01), None
E.B. Pedersen, “Synthesis of 2,4-bis(dimethylamino)quinolines by hmpt induced ring closure of anthranilates,” Tetrahedron Letters, p. 217-220, (Feb. 23, 1977).
Jorgen A. Jensen et al., “New One-step Synthesis of 2,4-bis(dialkylamino)quinoines and 4,6-bis(dialkylamino)thieno[2,3-b]pyridines,” Chemica Scripta, vol. 28 (No. 4), p. 435-437, (Feb. 23, 1988).

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