Preparation of biologically active molecules

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S069500, C435S071100, C435S471000, C435S325000, C435S252100, C435S320100, C530S351000, C536S023500

Reexamination Certificate

active

07098002

ABSTRACT:
Biologically active molecules are produced from their biologically inactive precursors by mutation of their native cleavage site to a site which is capable of being cleaved by a protease, and cleavage of the mutated molecule to yield a biologically active molecule.

REFERENCES:
patent: 0 646 646 (1995-04-01), None
patent: 1013763 (2000-06-01), None
patent: WO 93/13208 (1993-07-01), None
patent: WO 9313208 (1993-07-01), None
patent: WO 9724441 (1997-07-01), None
patent: WO 9838317 (1998-09-01), None
patent: WO 9907851 (1999-02-01), None
Ghayur et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature, vol. 386, Apr. 1997, pp. 619-623.
Ushio et al, Cloning of the cDNA for Human IFN-gamma Inducing Factor Expression inE. coliand Studies on the Biological activities of the Protein. The Journal of Immunlogy, vol. 156, pp. 4274-4279, 1996.
Callard et al. The Cytokine FactsBook, pp. 31-34, 1995.
Shimpei et al.J. Immunology, vol. 156 (11) 4274-4279 (1996).
Yong et al.,Science, vol. 275, (5297) 206-209 (1997).
C. Dinarello,Cytokine and Growth Factor Reviews, vol. 8 (4) 253-265 (Dec. 1997).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Preparation of biologically active molecules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of biologically active molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of biologically active molecules will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3702606

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.