Pharmaceutical composition comprised of spider venoms, the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S002600, C424S538000, C424S094620, C424S094600

Reexamination Certificate

active

06998389

ABSTRACT:
The present invention describes pharmaceutically effective substances from the poison of spiders of the family of Sicariidae as well as their preparation and their use in medicine.

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patent: 5196193 (1993-03-01), Carroll
patent: WO 95/19989 (1995-07-01), None
Bettini, Sergio (ed.),Arthropod Venoms, pp. 251-260.Handbuch der experimentellen Pharmakologie(Handbook of Experimental Pharmacology), vol. 48 (1978).
Burda, R. et al. “Zellzerstörende Giftkomponenten von Spinnen der Gattung Sicarius bei der Therapie von Tumorkrankungen (Cell Destructive Toxic Components of Spiders of the Genus Sicarius for Tumor Therapy).”Årztezeitschrift für Naturheilverfahren41, 3, pp. 172-177 (2000).
Geren, Collis R. et al. “Isolation and Characterization of Toxins from Brown Recluse Spider Venom (Loxosceles reclusa).”Archives of Biochemistry and Biophysics174, pp. 90-99 (1976).
Kurpiewski, Gretchen et al. “Platelet Aggregation and Sphingomyellnase D Activity of a Purified Toxin from the Venom of Loxosceles Reclusa.”Toxicology, vol. 96, pp. 166-167 (1982).
Merchant, Michael et al. “Observation of Phospholipase Activity in the Venom of the Brown Recluse Spider (Loxosceles Reclusa) by Phosphorous-31 NMR.”FASEB Journal, vol. 9, No. 6, p. A1313. Meeting Info: Annual Meeting of the American Society for Biochemistry and Molecular Biology, San Francisco, California, May 21-25, 1995.
Suárez, Gerardo et al. “Effect Extracts of the Venom Gland of the Recluse Spider,Loxosceles Laela, on Human Cells in Culture.”Toxicon, vol. 14, pp. 335-337 (1976).
Wright, R.P. et al. “Hyaluronidase and Esterase Activities of the Venom of the Poisonous Brown Recluse Spider.”Archives of Biochemistry and Biophysics159, pp. 415-426 (1973).

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