Pyrrolotriazine compounds

Details Pyrrolotriazine compounds Pyrrolotriazine compounds

2006-12-19

2006-12-19

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C514S243000

Reexamination Certificate

active

07151176

ABSTRACT:
The present invention provides compounds of formula Iand pharmaceutically acceptable salts thereof.The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

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