Estrogen agonist/antagonist metabolites

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reissue Patent

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Details

C514S428000, C514S567000, C548S543000, C548S576000

Reissue Patent

active

RE039419

ABSTRACT:
This invention relates to compounds that are mammalian metabolites of (−)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalene-2-ol. The compounds of the invention can be used as standards for analytical assays or as intermediates for the further chemical synthesis or biosynthesis of chemical entities. The invention also relates to pharmaceutical compositions for the treatment of disease and methods of treating disease.

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Wang, Lancet, 363, 910, Mar. 20, 2004.
Partial Translation of JP 2000-72771.

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