Antifungal agent and method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549513, 549553, C07D30302

Patent

active

048682080

ABSTRACT:
Novel semi-synthetic antifungal compounds which may be produced from 10-[(3-chloro-4-methoxyphenyl)methyl]-6- methyl-3-(2-methylpropyl)-16-[1-(3-phenyloxiranyl)ethyl]-1,4-dioxa- 8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone isolated from the fermentation of a cyanobacterium (Nostoc sp.) are described.

REFERENCES:
Kupchan et al., J. Am. Chem. Soc., 94, 1354 (1972).

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