Expression vector containing urea cycle enzyme gene,...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Rodent cell – per se

Reexamination Certificate

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C435S358000, C435S320100, C536S023500, C536S023100, C536S023200

Reexamination Certificate

active

07118913

ABSTRACT:
The present invention relates to expression vectors containing in vivo urea cycle enzyme gene; transformants thereof; and the use of transformants for protein overexpression. During the overexpression of protein, if the animal cell transformed with expression vectors of the present invention is used, amounts of ammonia accumulation within cell culture medium will decrease and cell growth rate will increase, thus, it is advantageous to be capable of obtaining desired protein in high yields.

REFERENCES:
patent: WO 97/30167 (1997-08-01), None
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