Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1983-09-26
1985-04-23
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
549426, 549396, 549387, 549338, 549337, 549336, 549427, 536 54, 260456A, 514459, 514517, A61K 3135, C07D31178, C07D31194, C07D30906
Patent
active
045130060
ABSTRACT:
Sulfamates of the following formula (I): ##STR1## wherein X is O or CH.sub.2 and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as herein defined have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and intermediates form part of the present invention.
REFERENCES:
patent: 4075351 (1978-02-01), Hirsch
N. K. Kochetkov, et al., in Zhurnal Obshchei Khimii, vol. 41, No. 8, pp. 1866-1871, (1971).
N. K. Kochetkov, et al., in Journal of General Chemistry of the USSR 42 (12) 2755-2757 (1972).
N. K. Kochetkov, et al., in Journal of General Chemistry of the USSR 44 (4) 871-875 (1974).
N. K. Kochetkov, et al., in Doklady Akademii Nauk SSSR, vol. 216, No. 1, pp. 97-100, (1974).
Tetrahedron Letters No. 36, pp. 3365-3368, Pergamon Press Ltd. (1978) by T. Tsuchiya.
J. Med. Chem. 1981, 24, 901-903, A. F. Hirsch.
Gardocki Joseph F.
Maryanoff Bruce E.
Chan Nicky
Levy David J.
McNeil Lab., Inc.
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