Botulinum neurotoxin-substance P conjugate or fusion protein...

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C435S069100, C435S325000, C424S236100, C424S239100, C536S023700, C530S350000, C514S002600, C514S012200

Reexamination Certificate

active

07056729

ABSTRACT:
Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.

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