Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-02-28
2006-02-28
Parkin, Jeffrey S. (Department: 1648)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387300, C530S388150, C530S388730, C530S388750, C435S070210, C435S455000, C435S326000, C435S328000, C435S334000, C435S343100, C435S320100, C424S133100, C424S135100, C424S139100, C424S141100, C424S142100, C424S143100
Reexamination Certificate
active
07005503
ABSTRACT:
Compositions are provided that comprise antibody against coreceptors for human immunodeficiency virus such as CCR5 and CXCR4. In particular, monoclonal human antibodies against human CCR5 are provided that bind to CCR5 with high affinity and are capable of inhibiting HIV infection at low concentrations. The antibodies can be used as prophylactics or therapeutics to prevent and treat HIV infection, for screening drugs, and for diagnosing diseases or conditions associated with interactions with HIV coreceptors.
REFERENCES:
patent: 5869250 (1999-02-01), Cheng et al.
patent: WO 99/28502 (1999-06-01), None
Frazer, J. K., and J. D. Capra, 1999, “Immunoglobulins: structure and function”, in Fundamental Immunology, Fourth Edition, William E. Paul, ed., Lippincot-Raven Publishers, Philadelphia, pp. 41-43 and 51-52.
Ueda, M. et.al., “Genetic Immobilization of Proteins on the Yeast Cell Surface,”Biotechnology Advances(2000) vol. 18, pp. 121-140.
Hua Shaobing
Pauling Michelle H.
Zhu Li
Genetastix Corporation
Parkin Jeffrey S.
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