Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Reexamination Certificate
2006-11-07
2006-11-07
Kemmerer, Elizabeth (Department: 1649)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
C530S300000, C530S388230, C530S350000, C530S380000, C530S395000, C530S391300, C435S007210, C435S069500, C435S252300, C435S320100, C436S501000, C424S130100, C424S178100, C424S085100
Reexamination Certificate
active
07132508
ABSTRACT:
A novel CC chemokine which is from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokine. A chemokine receptor is also provided. Methods of using said reagents and diagnostic kits are also provided.
REFERENCES:
patent: 5504003 (1996-04-01), Li et al.
patent: 5770402 (1998-06-01), Beutler et al.
patent: WO 96/22371 (1996-07-01), None
patent: WO 96/34891 (1996-11-01), None
Benjamini-E et al., eds, Immunology : A Short Course (1988).
Alexander et al., Proc. Natl. Acad. Sci. 89(3352-3356)1992.
Sticht et al. Biochemistry 38(5995-6002)1999.
Pardigol et al., PNAS 95(6308-6313)98.
Bacon et al., “IL-8-induced signal transduction in T lymphocytes involves receptor-mediated activation of phospholipases C and D,”J Immunol, 154(8):3654-3666 (1995).
Bacon et al., “Contrasting in vitro lymphocyte chemotactic activity of the hydroxyl enantiomers of 12-hydroxy-5,8,10,14-eicosatetraenoic acid,”Br J Pharmacol, 95(3):966-974 (1988).
Berger et al., “The gene for C10, a member of the β-chemokine family, is located on mouse chromosome 11 and contains a novel second exon not found in other chemokines,”DNA Cell Biol, 12(9):839-847 (1993).
Berridge, “Inositol triphosphate and calcium signaling,”Nature, 361(6410):315-325 (1993).
Billah and Anthes, “The regulation and cellular functions of phosphatidylcholine hydrolysis,”Biochem J, 269(2):281-291 (1990).
Danoff et al., “Cloning, genomic organization, and chromosomal localization of theScya5gene encoding the murine chemokine Rantes,”J Immunol, 152(3):1182-1189 (1994).
Groneborn and Clore, “Modeling the three-dimensional structure of the monocyte chemo-attractant and activating protein MCAF/MCP-1 on the basis of the solution structure of interleukin-8”Protein Eng, 4(3):263-269 (1991).
Hara et al., “Molecular cloning and functional characterization of a novel member of the C-C chemokine family,”J Immunol, 155(11):5352-5358 (1995).
Kelner et al., “Lymphotactin: a cytokine that represents a new class of chemokine,”Science, 266(5189):1395-1399 (1994).
Lodi et al., “High-resolution solution structure of the beta chemokine hMIP- beta by multidimensional NMR,”Science, 263(5154):1762-1767 (1994).
Matsushima and Oppenheim, “Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF, ”Cytokine, 1(1):2-13 (1989).
Miller and Krangel, “The human cytokine I-309 is a monocyte chemoattractant,”Proc Natl Acad Sci USA, 89(7):2950-2954 (1992).
Miller et al., “Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines,”Crit Rev Immunol, 12(1-2):17-46 (1992).
Oppenheim et al., “Properties of the novel proinflammatory supergene ‘intercrine’ cytokine family,”Annu Rev Immunol, 9:617-648 (1991).
Orlofsky et al., “Selective induction of the beta chemokine C10 by IL-4 in mouse macrophages,”J Immunol, 152(10):5084-5091 (1994).
Thompson (Ed.),The Cytokine Handbook, Schall, “The Chemokines,” pp. 419-460, 2nded., The Academic Press Inc., San Diego, CA (1994).
Schall and Bacon, “Chemokines, leukocyte trafficking, and inflammation,”Curr Opin Immunol, 6(6):865-873 (1994).
Schall, “Biology of the Rantes/Sis cytokine family,”Cytokine, 3(3):165-183 (1991).
Schall et al., “Human macrophage inflammatory protein alpha (MIP-1 alpha) and MIP-1 beta chemokines attract distinct populations of lymphocytes,”J Exp Med, 177(6):1821-1826 (1993).
Stoeckle and Barker, “Two-burgeoning families of platelet factor 4-related proteins: mediators of the inflammatory response,”New Biol, 2(4):313-323 (1990).
Wilson et al., “Clustering of cytokine genes on mouse chromosome 11,”J Exp Med, 171(4):1301-1314 (1990).
Neote et al., “Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor,”Cell, 72(3):415-425 (1993).
Hillier et al.,GenBank, Accession No. R91733, Aug. 25, 1995. The WashU-Merck EST project.
Hillier et al.,GenBank, Accession No. R96668, Sep. 11, 1995. The WashU-Merck EST project.
Hillier et al.,GenBank, Accession No. H62013, Oct. 6, 1995. The WashU-Merck EST project.
Hillier et al.,GenBank, Accession No. H54642, Sep. 21, 1995. The WashU-Merck EST project.
Poltorak et al., “MIP-1-gamma: molecular cloning, expression, and biological activities of a novel CC chemokine that is constitutively secretedin vivo,” J Inflamm, 45(3):207-219 (1995).
Combadiere et al., “Cloning and functional expression of a human eosinophil CC chemokine receptor,”J Biol Chem, 270(28)16491-16494 (1995).
Poltorak et al., “MIP-1-gamma: a novel neutrophil-activating, pyrogenic CC chemokine that circulates in plasma at pharmacologically active concentrations,”J Invest Med, 43(Suppl 2):364A (1995).
Poltorak et al., “Molecular cloning of MIP-1-gamma, a new member of the chemokine family, through differential screening based on extinction of macrophage-specific genes,”Clin Res, 42(2):306A (1994).
Youn et al., “A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors,”J Immunol, 155(5):2661-2667 (1995).
Pardigol et al., “HCC-2, a human chemokine: gene structure , expression pattern, and biological activity,”Proc Natl Acad Sci USA, 95(11):6308-6313 (1998).
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W25941, citing: WO 9721812 A2 dated 970619; US 95-567882 dated 951208; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W07202, citing: WO 9634891 A1 dated 961107; US 95-446881 dated 950505; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 96P-W05186, citing: WO 9632481 A1 dated 961017; US 95-42114 dated 950413; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 96P-W38170, citing: WO 9741230 A2 dated 971106; DE 96-19617312 dated 960430; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W25942, citing: WO 9721812 A2 dated 970619; US 95-567882 dated 951208; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W38170, citing: WO 9741230 A2 dated 971106; DE 96-19617312 dated 960430; “Search record pertaining to mouse CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W25942, citing: WO 9721812 A2 dated 970619; US 95-567882 dated 951208; “Search record pertaining to mouse CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 96P-W07202, citing: WO 9634891, A1 dated 961107; US 95-446881 dated 950505; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 96P-W05186, citing: WO 9632481 A1 dated 961017; US 95-421144 dated 950413; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 95P-R76126, citing: WO 9517092 A1 dated 950629; US 94-208339 dated 940308; “Search record pertaining to mouse CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W17663, citing: WO 9715594 A1 dated 970501; US 95-6051 dated 951024; “Search record pertaining to human CCF-18, performed in Jul. 1998”.
Derwent Geneseq Patent Sequence Database, Accession No. 97P-W16315, citing: WO 9712041 A1 dated 970403; US 95-4517, dated 950929; “Search r
Dairaghi Daniel J.
Hara Takahiko
Miyajima Atsushi
Schall Thomas J.
Wang Wei
Brannock Michael
Kemmerer Elizabeth
Schering Corporation
Triolo Thomas A.
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