Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Reexamination Certificate
2006-08-08
2006-08-08
Andres, Janet L. (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
C435S004000
Reexamination Certificate
active
07087400
ABSTRACT:
This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be controlled, and to useful therapeutic effects which may be obtained as a result of such control. More specifically, but not exclusively, the invention is concerned with interconversion between cortisone and cortisol in humans.
REFERENCES:
Lakshmi et al.,Endocrinology, vol. 128, pp. 1741-1748, 1991.
Gomez-Sanchez et al.,Am. J. Physiology, vol. 263, pp. E1125-1130, 1992.
Edwards Christopher Richard Watkin
Seckl Jonathan Robert
Walker Brian Robert
Andres Janet L.
Collison Angela M.
Frommer & Lawrence & Haug LLP
Gucker Stephen
Kowalski Thomas J.
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