Microfluidic device with multiple microcoil NMR detectors...

Electricity: measuring and testing – Particle precession resonance – Spectrometer components

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C324S306000

Reexamination Certificate

active

07141978

ABSTRACT:
An NMR system comprises an NMR probe comprising multiple NMR detection sites. Each of the multiple NMR detection sites comprises a sample holding void and an associated NMR microcoil. The NMR system further comprises a controllable fluid router operative to direct fluid sample to the multiple NMR detection sites.

REFERENCES:
patent: 5304487 (1994-04-01), Wilding et al.
patent: 5654636 (1997-08-01), Sweedler et al.
patent: 5684401 (1997-11-01), Peck et al.
patent: 5928880 (1999-07-01), Wilding et al.
patent: 6026316 (2000-02-01), Kucharczyk et al.
patent: 6061587 (2000-05-01), Kucharczyk et al.
patent: 6097188 (2000-08-01), Sweedler et al.
patent: 6103199 (2000-08-01), Bjornson et al.
patent: 6194900 (2001-02-01), Freeman et al.
patent: 6456072 (2002-09-01), Webb et al.
patent: 6696838 (2004-02-01), Raftery et al.
patent: 6700379 (2004-03-01), Peck et al.
patent: 6822454 (2004-11-01), Peck et al.
patent: 6958609 (2005-10-01), Raftery et al.
patent: 2002/0105327 (2002-08-01), Peck et al.
patent: 2002/0130661 (2002-09-01), Raftery et al.
patent: 2002/0149369 (2002-10-01), Peck et al.
patent: 2004/0164738 (2004-08-01), Raftery et al.
patent: 2005/0030033 (2005-02-01), Peck et al.
patent: 2005/0253587 (2005-11-01), Peck et al.
patent: WO-0050924 (2000-08-01), None
patent: WO 02/056049 (2002-07-01), None
Wu et al. (1994) Nanoliter Volume Sample Cells for1H NMR: Application to On-Line Detection in Capillary Electrophoresis, Journal of the American Chemical Society V. 116, No. 17, pp. 7929-7930.
Olson et al (1995) High-Resolution Microcoil1H-NMR for Mass-Limited, Nanoliter-Volume Samples, Science, vol. 270, pp. 1967-1970.
Peck et al (1995) Design and Analysis of Microcoils for NMR Microscopy, Journal of Magnetic Resonance, Series B 108, pp. 114-124.
Peck et al (1994) NMR Microspectroscopy Using 100 μm Planar RF Coils Fabricated on Gallium Arsenide Substrates, IEEE Trans. Biomed. Eng. 41(7) 706-709.
Stocker et al (1997) Nanoliter Volume, High-Resolution NMR Microspectroscopy Using a 60-μm Planar Microcoil, IEEE Trans Biomed. Eng. 44 (11) 1122-1127.
Magin et al (1997) Miniature Magnetic Resonance Machines, IEEE Spectrum, vol. 34, No. 10, 51-61.
Trumbull et al (1998) Integrating Microfluidic Systems and NMR Spectroscopy: Preliminary Results, Solid-State Sensor and Actuator Workshop Hilton Head Island, South Carolina, Jun. 8-11.
Trumbull et al (2000) Integrating Microfabricated Fluidic Systems and NMR Spectroscopy, 47(1) 1-6.
Haner et al (2000) Small Volume Flow Probe for Automated Direct-Injection NMR Analysis: Design and Performance, Journal of Magnetic Resonance 143, pp. 69-78.
Li et al (1999) Multiple Solenoidal Microcoil Probes for High-Sensitivity, High-Throughput Nuclear Magnetic Resonance Spectroscopy, Anal. Chem. 71, pp. 4815-4820.
Fisher et al (1999) NMR Probe for the Simultaneous Acquisition of Multiple Samples, Journal of Magnetic Resonance 138, pp. 160-163.
Huang et al (1998) Digitally Controlled Electrophoretic Focusing, Analytical Chemistry 71 (8) 1628-1632.
Koegler et al (1996) Focusing Proteins in an Electric Field Gradient, Journal of Chromatography A, 229 pp. 229-236.
Koegler et al (1996) Field Gradient Focusing: A Novel Method for Protein Separation, American Chemical Society.
Hou et al (2000) Analysis of Multiple Samples Using Multiplex Sample NMR: Selective Excitation and Chemical Shift Imaging Approaches, Analytical Chemistry.
Bayer et al (1979) On-Line Coupling of High-Performance Liquid Chromatography and Nuclear Magnetic Resonance, Journal of Chromatography 188, pp. 497-507.
Watanabe et al (1978) Direct-Coupling of FT-NMR to High Performance Liquid Chromatography, Proc. Japan Acad., vol. 54, Ser. B.
Dechow, J. et al.: (2000) “Fabrication of NMR Microsensors for Nanoliter Sample Volumes”, vol. 53, pp. 517-519.
Written Opinion Dated Jun. 6, 2003, based on PCT/US01/46733.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Microfluidic device with multiple microcoil NMR detectors... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microfluidic device with multiple microcoil NMR detectors..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microfluidic device with multiple microcoil NMR detectors... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3672491

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.