Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-12-05
2006-12-05
Zara, Jane (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S006120, C435S091100, C435S091310, C536S023100, C536S024310, C536S024330
Reexamination Certificate
active
07144999
ABSTRACT:
Compounds, compositions and methods are provided for modulating the expression of hypoxia-inducible factor 1 alpha. The compositions comprise oligonucleotides, targeted to nucleic acid encoding hypoxia-inducible factor 1 alpha. Methods of using these compounds for modulation of hypoxia-inducible factor 1 alpha expression and for diagnosis and treatment of disease associated with expression of hypoxia-inducible factor 1 alpha are provided.
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Dobie Kenneth W.
Ward Donna T.
Isis Pharmaceuticals , Inc.
Isis Pharmaceuticals Inc. Patent Department
Zara Jane
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