Peptides and polypeptides useful for regenerating the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S002600, C530S324000, C530S300000, C530S322000, C530S323000, C435S375000

Reexamination Certificate

active

06995140

ABSTRACT:
The invention concerns in particular novel peptides and polypeptides comprising at least the following sequence in amino acids: -W-S-A1-C-S-A2-C-G- in which A1 and A2 are amino acid sequences comprising 1 to 5 amino acids, useful as medicines in therapeutic treatments involving the regeneration of the nervous system cells, for treating neuroblastomas, and also useful as additives in the culture of nervous cells.

REFERENCES:
patent: 443 404 (1991-08-01), None
patent: 93/00430 (1993-01-01), None
patent: 94/06464 (1994-03-01), None
Skolnick et al., 2000, Tibtech, vol. 18, pp. 34-49.
Bork et al., 1998, Current Opinion in Structural Biology, vol. 8, pp. 331-332.
Hoffer et al., 1997, J. Neural transm., vol. 49, pp. 1-10.
A. Klar et al., “F.-Spondin” A Gene Expressed at High Levels . . . and Nuerite Extension, Cell, vol. 69, Apr. 1992, pp. 95-110, XP 002059005.
S. Gobron et al., “SCO-Spondin: a new member of the thrombospondin . . . of neuronal aggregation”, J. of Cell Sci., 1996, pp. 1053-1061, XP 002059006.
G. Mor et al., “Induction of Neonatal Tolerance by Plasmid DNA Vaccination of Mice”, J. Clinical Invest., vol. 98:12, Dec. 1996, pp. 2700-2705, XP 002084526.

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