Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-08-08
2006-08-08
Tsang, Cecilia J. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S247000, C514S256000, C514S319000, C514S365000, C514S372000, C514S374000, C514S378000, C514S385000, C514S396000, C514S438000, C514S461000, C514S640000, C514S680000, C544S154000, C544S268000, C544S294000, C544S381000, C546S196000, C546S204000, C546S285000, C546S302000, C548S196000, C548S206000, C548S215000, C548S300100, C548S347100, C548S529000, C549S078000, C549S080000, C549S497000, C564S226000, C564S267000, C568S326000, C568S733000
Reexamination Certificate
active
07087599
ABSTRACT:
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynacomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.
REFERENCES:
patent: 4316043 (1982-02-01), Cragoe, Jr. et al.
patent: 4317922 (1982-03-01), Cragoe, Jr. et al.
patent: 4356313 (1982-10-01), Cragoe, Jr. et al.
patent: 4356314 (1982-10-01), Cragoe, Jr. et al.
patent: 4377354 (1983-03-01), Morton
patent: 4604396 (1986-08-01), Cragoe et al.
patent: 4675341 (1987-06-01), Cragoe, Jr.
patent: 4704472 (1987-11-01), Conn et al.
patent: 4731470 (1988-03-01), Pietruszkiewicz et al.
patent: 4731471 (1988-03-01), Cragoe, Jr. et al.
patent: 4731472 (1988-03-01), Pietruszkiewicz et al.
patent: 4797391 (1989-01-01), Woltersdorf, Jr. et al.
patent: 4835313 (1989-05-01), Pietruszkiewicz et al.
patent: 6251898 (2001-06-01), Cragoe et al.
Parker, Jr. Dann LeRoy
Ratcliffe Ronald W.
Wildonger Kenneth J.
Wilkening Robert R.
Beeler Nicole M.
Covington Raymond
Daniel Mark R.
Merck & Co. , Inc.
Tsang Cecilia J.
LandOfFree
Estrogen receptor modulators does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Estrogen receptor modulators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Estrogen receptor modulators will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3666607