Mitogens of leukocytes and inflamed tissues

Details Mitogens of leukocytes and inflamed tissues Mitogens of leukocytes and inflamed tissues

1982-03-15

1985-04-23

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 435 68, 514908, A61K 39395, A61K 3702, C07G 700, C12P 2100

Patent

active

045129711

ABSTRACT:
The invention relates to new mitogens of leukocytes and inflamed tissue which have the biological and physicochemical properties stated in the claims. The compounds selectively induce the division and differentiation of leukocytes and their precursors in the bone marrow. The invention also relates to a biotechnical process for preparing and isolating the mitogens and to pharmaceutical compositions containing them.

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Mochizuki et al., J. Immun. Methods, vol. 39, pp. 185-201, 1980.
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Glick, J., Fundamentals of Human Lymphoid Cell Culture, pp. 27-27, Marcel Dekker, Inc. New York, 1981.
Pick, E., Lymphokines, pp. 1-19, Academic Press, New York, 1981.
Clausen, J., J. Immunol., vol. 108, pp. 453-459, 1972.

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