Method for obtaining biologically active mucopolysaccharides of

Details Method for obtaining biologically active mucopolysaccharides of Method for obtaining biologically active mucopolysaccharides of

1987-10-19

1991-05-28

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C08B 3710

Patent

active

050196499

ABSTRACT:
Method for obtaining biologically active mucopolysaccharides by controlled depolymerization of heparin, wherein the quantity of products generating nitrous acid is selected so that those products are totally consumed when the desired depolymerization degree is reached.

REFERENCES:
patent: 4303651 (1981-12-01), Lindahl et al.
patent: 4351938 (1982-09-01), Barnett
patent: 4401662 (1983-08-01), Lormeau et al.
Shively et al., Formation of Anhydro Sugars in the Chemical Depolymerization of Heparin, Biochemistry 15 (18), pp. 3932-3942 (1976).
Cifonelli, Nitrous Acid Depolymerization of Glycosaminoglycans, Chem. Abstracts 85:89445z (1976).

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