Indazolecarboxamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514212, 5142345, 514255, 514307, 514403, A61K 31445

Patent

active

057983674

ABSTRACT:
Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.

REFERENCES:
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Taniyama et al. "Cisapride stimulates motility of the instetine via the 5HT receptors" Embase abst. No. 91337334, 1991.
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Gidener et al. "Influence of serotnin on the human ureter . . . " Medline Abst. 96160103, 1996.
Miyashita et al. "A novel specific 5HT4 receptor . . . " Derwent Drug Abst. 92-33552, 1995.
Robert W. Hamilton, J. Heterocyclic Chem., 13, 545-553.
Kaumann, et al., Bio. Med. Chem. Let., 2, 419-420 (1992).
Derwent Abstract, Belgium 770068 (1970).
Derwent Abstract, Japanese 8081-858 (1972).

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