Substituted imidazole compounds

Details Substituted imidazole compounds Substituted imidazole compounds

1998-07-01

2000-04-04

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544316, A61K 31505, C07D40304

Patent

active

060462086

ABSTRACT:
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.

REFERENCES:
patent: 2748119 (1956-05-01), Rorig
patent: 3557114 (1971-01-01), Bicking
patent: 3707475 (1972-12-01), Lombardino
patent: 3772441 (1973-11-01), Lombardino
patent: 3929807 (1975-12-01), Fitzi
patent: 3940486 (1976-02-01), Fitz
patent: 4058614 (1977-11-01), Baldwin
patent: 4175127 (1979-11-01), Bender et al.
patent: 4199592 (1980-04-01), Cherkofsky
patent: 4447431 (1984-05-01), Sallmann
patent: 4503065 (1985-03-01), Wilkerson
patent: 4565875 (1986-01-01), Cavender
patent: 4585771 (1986-04-01), Klose et al.
patent: 4686231 (1987-08-01), Bender et al.
patent: 4822805 (1989-04-01), Tasasugi et al.
patent: 5593991 (1997-01-01), Adams et al.
patent: 5593992 (1997-01-01), Adams et al.
patent: 5656644 (1997-08-01), Adams et al.
patent: 5658903 (1997-08-01), Adams et al.
patent: 5663334 (1997-09-01), Adams et al.
patent: 5670527 (1997-09-01), Adams et al.
patent: 5686455 (1997-11-01), Adams et al.
patent: 5739143 (1998-04-01), Adams et al.
patent: 5756499 (1998-05-01), Adams et al.
patent: 5864036 (1999-01-01), Adams et al.
Dinarello et al., Rev. Infect. Disease, 6, p. 51 (1984).
Dinarello, J. Clin. Immun., 5(5), p. 287-297 (1985).
R.P. Soni, Aust. J. Chem., 35, p. 1493-6 (1982).
Poli et al., Proc. Nat'l. Acad. Sci., 87, p. 782-784 (1990).
VanLeusen et al., J. Org. Chem., 42, p. 1153 (1977).
Kumada et al., Tetrahedron Letters, 22, p. 5319 (1981).
Pridgen, J. Org. Chem., 47, p. 4319 (1982).
Stille, J. Amer. Chem. Soc., 109, p. 5478 (1978).
Fischer et al., Rec. Trav. Chim. Pays. Bas., 84, p. 439 (1965).
Snieckus, V. Tetrahedron Letters, 29, p. 2135 (1988).
Terashimia, M., Chem. Pharm. Bull., 11, p. 4755 (1985).
Thompson, W.J. et al., J. Org. Chem., 49, p. 5237 (1984).
Garigipati, R., Tetrahedron Letters, 31, p. 190 (1989).
Engel & Steglich, Liebigs Ann. Chem., p. 1916 (1978).
Strzybyl et al., J. Org. Chem., 28, p. 3381 (1963).
Zavyalov, et al., Khim Farm Zh, 26(3), p. 88 (1992) (With Translation).
Colotta et al., J. Immunol., 132(2), p. 936 (1984).
Simon et al., J. Immunol. Methods, 84, p. 85 (1985).
Becker et al., Immunol., 147, p. 4307 (1991).
Gilbert, Synthesis, pp. 30-32 (1972).
Morton et al., Tetrahedron Letters, p. 4123 (1982).
Armarego, W., J. Chem. Soc., (JCSOA9) p. 561 (1962).
Kawasaki et al., J. Bio. Chem. 272(30), p. 18518-18521.
Uno. Bull. Chem. Soc. Japan., 69, p. 1763-1767 (1996).
Katrutzky, Synthesis, p. 45-47 (1993).
Johnson, P.A., J. Chem. Soc., Perkin Trans. 1, p. 895-905 (1996).
Ishibashi, Chem. Pharm. Bull., 37(8), p. 2214-2216 (1989).

Affiliated with

Also associated with

Rating

Substituted imidazole compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted imidazole compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted imidazole compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-365543