Modified carrier particles for use in dry powder inhalers

Details Modified carrier particles for use in dry powder inhalers Modified carrier particles for use in dry powder inhalers

2006-11-07

2006-11-07

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S400000, C424S489000

Reexamination Certificate

active

07132115

ABSTRACT:
The invention relates to carrier particles for use in pharmaceutical compositions for the pulmonary administration of medicaments by means of dry powder inhalers. In particular, the invention relates to a novel technological process for obtaining a carrier modified so as to improve the efficiency of redispersion of active particles and hence increase the respirable fraction. After the treatment of the invention, the surface of said modified carrier particles can also be coated with a suitable additive so as to further improve the respirable fraction.

REFERENCES:
patent: 6153224 (2000-11-01), Staniforth
patent: 6284287 (2001-09-01), Sarlikiotis et al.
patent: 6528096 (2003-03-01), Musa et al.
patent: 6641844 (2003-11-01), Musa et al.
patent: 44 25 255 (1996-01-01), None
patent: 2 107 715 (1983-05-01), None
patent: WO 95/11666 (1995-05-01), None
patent: WO 96/23485 (1996-08-01), None
patent: WO 00/28979 (2000-05-01), None
Herbert A. Lieberman et al,Pharmaceutical Dosage Forms, vol. 2, 1981, Marcel Dekker, Inc., pp. 29-43.

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