Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-25
1998-08-25
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514210, 514212, 540481, 540597, 544359, 544360, 544372, A61K 31495, A61K 31395, C07D40100, C07D40300
Patent
active
057983593
ABSTRACT:
The invention relates to compounds of the formulas ##STR1## wherein Z, R.sub.c, y, x, l.sub.1, l.sub.2, l.sub.3, u, R.sub.4, R.sub.c', n, R.sub.1, R.sub.2, and R.sub.3, are as described herein. These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.
REFERENCES:
patent: 5350852 (1994-09-01), Eonds-Alt et al.
patent: 5464788 (1995-11-01), Bock et al.
patent: 5589489 (1996-12-01), Shenvi et al.
patent: 5607936 (1997-03-01), Chiang et al.
Blythin David J.
Chen Xiao
Piwinski John
Shih Neng-Yang
Shue Ho-Jane
Coleman Brenda
Magatti Anita W.
Schering Corporation
Shah Mukund J.
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