Use of adamantyl-substituted polycyclic acetylene compounds in s

Details Use of adamantyl-substituted polycyclic acetylene compounds in s Use of adamantyl-substituted polycyclic acetylene compounds in s

1996-07-02

1998-08-25

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

424 60, 424 69, 424 701, 514356, 514430, 514546, 514569, 514617, 514700, 514719, 514844, 514880, A61K 706, A61K 748, A61K 3119, A61K 31535

Patent

active

057983542

ABSTRACT:
Novel pharmaceutically/cosmetically-active adamantyl-substituted polycyclic acetylene compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(f): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

REFERENCES:
Chemical Abstracts, vol. 87, No. 3, Jul. 18, 1977, Columbus, Ohio; abstract No. 22693b, Musantaeva, Sh. et al, "Synthesis of P-Acetylenylbenzoic Acid", p. 599, Col. 2; & Deposited Doc., 1974, pp. 297-375, VINTI.

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