Regulation of human eosinophil serine protease 1-like enzyme

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S006120, C435S069100, C435S252300, C435S254230, C435S320100

Reexamination Certificate

active

07060810

ABSTRACT:
A human eosinophil serine protease 1-like enzyme, cDNA, and reagents that regulate the enzyme can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, asthma, COPD, airway allergy, and osteoporosis.

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Hoopen J. D. et al., “Testisin, A New Human Serine Proteinase Expressed by Premeiotic Testicular Germ Cells And Lost in Testicular Germ Cell Tumors”, Cancer Research, Baltimore MD., vol. 59, Jul. 1, 1999; pp. 3199-3205.; Abstract XP002924343.
Masahiro Inoue, et al.; “Cloning and Tissue Distribution of a Novel Serine Protease esp-l from Human Eosinophils” Biochemical And Biophysical Research Communications vol. 252, 307-312 (1998) Article No. RC989645.
Masahiro Inoue, et al.; Structural Analysis of esp-1 Gene (PRSS 21): Biochemical and Biophysical Research Communications vol. 266, pp. 564-568 (1999); Article ID bbrc. 1999.1870.

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