Controlled release preparation of insulin and its method

Details Controlled release preparation of insulin and its method Controlled release preparation of insulin and its method

2006-08-08

2006-08-08

Chen, Shin-Lin (Department: 1632)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S409000, C424S418000, C424S489000, C424S497000

Reexamination Certificate

active

07087246

ABSTRACT:
A controlled release preparation of insulin and its method are provided. The controlled release preparation of insulin contains microparticles obtained by microencapsulation of uniform microcystals of insulin using biodegradable polymeric materials. Since the denaturation of insulin that may occur during microencapsulation is reduced, the stability of the preparation can be increased. Also, the ratio of insulin to a polymer carrier is increased, which is suitable for pulmonary delivery. Further, the controlled release preparation of insulin can continuously exhibit pharmaceutical efficacy in vivo in a stable manner for an extended period of time.

REFERENCES:
patent: 9-315997 (1997-12-01), None
patent: WO 99/55310 (1999-11-01), None

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