Immunoeffector compounds

Details Immunoeffector compounds Immunoeffector compounds

2006-10-31

2006-10-31

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S023000, C514S024000, C514S025000, C536S004100, C536S017200, C536S017300, C536S017500, C536S018700, C424S001730, C424S009430

Reexamination Certificate

active

07129219

ABSTRACT:
This invention provides compounds containing a 2-deoxy-2-amino-β-D-glucopyranose (glucosamine) glycosidically linked to a cyclic aminoalkyl (aglycon) group. The invention further provides methods for inducing an immune response using the compounds of the present invention in the presence or absence of an antigen. In addition, methods for treating disease with the compounds of the present invention with or without an antigen are also provided in this invention.

REFERENCES:
patent: 6013640 (2000-01-01), Elliott et al.
patent: 6525028 (2003-02-01), Johnson et al.
patent: WO 98/50399 (1998-11-01), None
Johnson, et al.; “Synthesis and Biological evaluation of a new class of vaccine adjuvants: Aminoalkyl glucosaminide 4-phosphates (AGPs)”;Bioorganic&Medicinal Chemistry Letters; 1999; pp. 2273-2278; vol. 9; Elsevier Science Ltd.

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