Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2006-05-23
2006-05-23
Gupta, Anish (Department: 1654)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S497000, C424S499000, C530S313000, C530S328000, C514S002600, C514S015800
Reexamination Certificate
active
07048947
ABSTRACT:
A sustained-release preparation which comprises a physiologically active peptide of general formulawherein X represents an acyl group;R1, R2and R4each represents an aromatic cyclic group;R3represents a D-amino acid residue or a group of the formulawherein R3′ is a heterocyclic group;R5represents a group of the formula —(CH2)n—R5′ wherein n is 2 or 3, and R5′ is an amino group which may optionally be substituted, an aromatic cyclic group or an O-glycosyl group;R6represents a group of the formula —(CH2)n—R6′ wherein n is 2 or 3, and R6′ is an amino group which may optionally be substituted;R7represents a D-amino acid residue or an azaglycyl residue; andQ represents hydrogen or a lower alkyl group, or a salt thereof and a biodegradable polymer having a terminal carboxyl group.The sustained-release preparation shows a constant release of the peptide over a long time and is substantially free from an initial burst.
REFERENCES:
patent: 1995970 (1935-03-01), Dorough
patent: 2362511 (1944-11-01), Teeters
patent: 2438208 (1948-03-01), Fllachione et al.
patent: 2703316 (1955-03-01), Schneider et al.
patent: 2758987 (1956-08-01), Saizberg
patent: 3043782 (1962-07-01), Jensen
patent: 3092553 (1963-06-01), Fisher et al.
patent: 3297033 (1967-01-01), Schmitt et al.
patent: 3523906 (1970-08-01), Vrancken et al.
patent: 3539465 (1970-11-01), Hiestand et al.
patent: 3565869 (1971-02-01), Deprospero
patent: 3636956 (1972-01-01), Schneider
patent: 3645911 (1972-02-01), van Besauw et al.
patent: 3691090 (1972-09-01), Kitajima et al.
patent: 3755553 (1973-08-01), Scribner et al.
patent: 3755558 (1973-08-01), Scribner
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3839297 (1974-10-01), Wasserman et al.
patent: 3882228 (1975-05-01), Boncey
patent: 3890283 (1975-06-01), Casey et al.
patent: 3912692 (1975-10-01), Casey et al.
patent: 3922338 (1975-11-01), Estevenel et al.
patent: 3956172 (1976-05-01), Saeki et al.
patent: 4137921 (1979-02-01), Okuzumi et al.
patent: 4234571 (1980-11-01), Nestor et al.
patent: 4249531 (1981-02-01), Heller et al.
patent: 4272398 (1981-06-01), Jaffe
patent: 4273920 (1981-06-01), Nevin
patent: 4341767 (1982-07-01), Nestor et al.
patent: 4384975 (1983-05-01), Fong
patent: 4389330 (1983-06-01), Tice et al.
patent: 4479911 (1984-10-01), Fong
patent: 4555399 (1985-11-01), Hsiao
patent: 4605730 (1986-08-01), Shalaby et al.
patent: 4622244 (1986-11-01), Lapka et al.
patent: 4637905 (1987-01-01), Gardner
patent: 4652441 (1987-03-01), Okada et al.
patent: 4675189 (1987-06-01), Kent et al.
patent: 4677191 (1987-06-01), Tanaka et al.
patent: 4710384 (1987-12-01), Rotman
patent: 4728721 (1988-03-01), Yamamoto et al.
patent: 4767628 (1988-08-01), Hutchinson
patent: 4849228 (1989-07-01), Yamamoto et al.
patent: 4853226 (1989-08-01), Machida et al.
patent: 4917893 (1990-04-01), Okada et al.
patent: 4933105 (1990-06-01), Fong
patent: 4954298 (1990-09-01), Yamamoto et al.
patent: 5036047 (1991-07-01), Mia
patent: 5110904 (1992-05-01), Haviv et al.
patent: 5140009 (1992-08-01), Haviv et al.
patent: 5171835 (1992-12-01), Janaky et al.
patent: 5187150 (1993-02-01), Speiser et al.
patent: 5192741 (1993-03-01), Orsolini et al.
patent: 5330767 (1994-07-01), Yamamoto et al.
patent: 5476663 (1995-12-01), Okada et al.
patent: 5480656 (1996-01-01), Okada et al.
patent: 5480868 (1996-01-01), Kamei et al.
patent: 5575987 (1996-11-01), Kamei et al.
patent: 5631020 (1997-05-01), Okada et al.
patent: 5631021 (1997-05-01), Okada et al.
patent: 5643607 (1997-07-01), Okada et al.
patent: 5665394 (1997-09-01), Igari et al.
patent: 5668111 (1997-09-01), Kamei et al.
patent: 5716640 (1998-02-01), Kamei et al.
patent: 5972891 (1999-10-01), Kamei et al.
patent: 5980947 (1999-11-01), Yamakawa et al.
patent: 6528093 (2003-03-01), Kamei et al.
patent: 1 169 090 (1982-08-01), None
patent: 0 052 510 (1982-05-01), None
patent: 0 058 481 (1982-08-01), None
patent: 0 107 591 (1984-05-01), None
patent: 0 145 240 (1985-06-01), None
patent: 0 172 636 (1986-02-01), None
patent: 0 178 824 (1986-04-01), None
patent: 0 182 262 (1986-05-01), None
patent: 0 190 833 (1986-08-01), None
patent: 0 202 065 (1986-11-01), None
patent: 0 302 582 (1989-02-01), None
patent: 0 442 671 (1991-02-01), None
patent: 0 461 630 (1991-12-01), None
patent: 0 467 389 (1992-01-01), None
patent: 0 481 732 (1992-04-01), None
patent: 0 586 238 (1994-03-01), None
patent: 2126270 (1972-02-01), None
patent: 2216720 (1972-02-01), None
patent: 2551072 (1985-03-01), None
patent: 929402 (1959-11-01), None
patent: 1405108 (1971-12-01), None
patent: 1351409 (1972-02-01), None
patent: 2088314 (1982-06-01), None
patent: 2145422 (1984-08-01), None
patent: 2209937 (1989-06-01), None
patent: 2246514 (1992-05-01), None
patent: SHO 40-500 (1965-01-01), None
patent: 55-114193 (1972-05-01), None
patent: 43-3017 (1973-02-01), None
patent: 63-218632 (1988-09-01), None
patent: 89/04673 (1989-06-01), None
patent: 98/35654 (1998-09-01), None
Ogawa et al. “A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid.” Chem. Pharm. Bull. Vo. 36. No. 3 pp. 1095-1103. 1988.
Arshady,R., “Preparation of biodegradable microspheres and microcapsules: 2. Polyactides and related Polyesters,”Journal of Controlled Release, vol. 17, 1991.
Bakan, J. A. et al., “Microencapsulation,”The Theory and Practice of Industrial Pharmacy, pp. 384-407, 1970.
Bodmeier et al., “Solvent selection in the preparation of poly(DL-lactide) microspheres prepared by the solvent evaporation method,”International Journal of Pharaceutics43:179-186 (1988) Elsevier.
Chang, T., “Biodegradable Semipermeable Microcapsules containing Enzymes, Hormones, Vaccines, and Other Biologicals,”Journal of Bioengineering, 1:25-31, 1976.
Dressler, et al., “Viable Prosthetic Interface,”J. Biomed. Mater. Res. Sympomium1:169-178 (1971).
English Abstract of Japanese Patent JP 43-3017.
Hutchinson et al.,Trends in Biotech5(4):102 (1987).
Journal of the Chemical Society of Japan, Industrial Chemistry Section, vol. 72, 1969 (Partial Translation).
Journal of the Chemical Society of Japan, Industrial Chemistry Section, 68(5):741-1018, 1965.
Keipert, S. et al., “Antiglaumakotosahaltige Ophthalmika mit prolongierter Wirkung auf Basis makromolekularer Hilfsstoffe,”Die Pharmazie, pp. 594-595 (English Abstract at p. 594), Aug. 1990.
Kondo, A.,Microcapsule Processing and Technology, Marcel Dekker, Inc., New York, New York (1979), Chapter 1, “Microcapsules—General Concepts,” pp. 1-10; Chapter III, “Applications and Studies of Microcapsules,” pp. 18-26; Chapter IV, “History and Classification of Microencapsulation,” pp. 27-34; Chapter X, “Microencapsulation Utilizing In-Liquid Drying Process (Complex Emulsion Method),” pp. 106-120.
Kulkarni et al, “Biodegradable Poly(lactic acid) Polymers,”Journal of Biomedical Materials Research, 5:169-181, 1971.
Kulkarni et al, “Polyactic Acid for Surgical Implants,”Archives of Surgery, 93(5):839-843, Nov. 1966.
Lewis, D. et al., “Controlled Release of Bioactive Agents from Lactide/Glycolide Polymers,”Biodegradable Polymers as Drug Delivery Systems, pp. 1-41, 1990.
Microcapsule, Industrial Technology, Library 25, pp. 102-103 (1971).
Ogawa, Y. et al, “Controlled Release of LHRH Agonist, Leuprolide Acetate, from Microcapsules: Serum Drug Level Profiles and Pharmacological Effects in Animals,”J. Pharma Pharmacol., pp. 439-444, 1989.
Okada, H. et al., “One-and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate,”Advanced Drug Delivery Reviews, 28:43-70, 1997.
Okada, H. et al., “One-month release injectable microspheres of leuprolide acetate inhibit steroidogenesis and genital organ growth in rats,”International Journal of Pharmaceutics, 54:231-239, 1989.
Okada, H. et al.,Critical Reviews in Therapeutic Dr
Igari Yasutaka
Kamei Shigeru
Ogawa Yasuaki
Foley & Lardner LLP
Gupta Anish
Takeda Pharmaceutical Company Limited
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