Glucose dehydrogenase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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Details

C435S440000, C435S004000, C435S006120, C435S026000, C435S069100, C435S071100, C435S252300, C435S320100, C536S023200, C536S023700

Reexamination Certificate

active

07067295

ABSTRACT:
Modified water-soluble glucose dehydrogenase having pyrrolo-quinoline quinone as a coenzyme are provided wherein at least one amino acid residue is replaced by another amino acid residue in a specific region. Modified water-soluble PQQGDHs of the present invention have improved thermal stability.

REFERENCES:
patent: A 78636 (1983-05-01), None
patent: A11-243949 (1999-09-01), None
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Yoshida et al., ProteinEng., vol. 12, No. 1, pp. 63-70 (1999).
Sode et al., J. Biotechnol., vol. 49, No. 103, pp. 239-243 (1996).

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