Method for the production of .alpha.-L-aspartyl-L-phenylalanine

Details Method for the production of .alpha.-L-aspartyl-L-phenylalanine Method for the production of .alpha.-L-aspartyl-L-phenylalanine

1994-08-02

1995-05-30

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C22900

Patent

active

054203384

ABSTRACT:
A method is disclosed for the production of .alpha.-APM HCl by treating an F-.alpha.-AP derivative with a mixed solvent of methanol, hydrochloric acid and water, wherein the solubility of .alpha.-APM HCl is lowered to increase the separation yield thereof.

REFERENCES:
patent: 4684745 (1987-08-01), Takemoto et al.
patent: 4897507 (1990-01-01), Takahashi et al.
patent: 5053532 (1991-10-01), Hill
patent: 5292923 (1994-03-01), Kato et al.
patent: 5304671 (1994-04-01), Abe et al.

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