Thiopyrano(2,3,4-c,d) indolyloxime ether alkylcarboxylates

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546270, C07D49508, A61K 3147, A61K 3144

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active

054202825

ABSTRACT:
Compounds of the structure ##STR1## wherein R.sup.1 is selected from the group consisting of ##STR2## are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.

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