Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-01-14
2000-03-07
Allen, Marianne P.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
435 696, 4353201, 435325, 4352523, 530350, 530380, 530381, A61K 3817, A61K 3836, C12N 1512
Patent
active
060340606
ABSTRACT:
The peptide of the present invention comprises a specific amino acid sequence including at least 118 amino acids and has the ability to promote the activation of protein C by thrombin. The peptide of the present invention can be produced efficiently on a large scale by recombinant DNA techniques. The peptide of the present invention has anticoagulant, platelet aggregation-inhibiting and thrombolytic activities, without exhibiting side effects such as bleeding and anaphylactic shock. Therefore, the peptide of the present invention can be effectively used for the treatment of various circulatory organ diseases, toxemia of pregnancy and the like.
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Suzuki Koji
Yamamoto Shuji
Allen Marianne P.
Asahi Kasei Kogyo Kabushiki Kaisha
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