Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-05-16
2006-05-16
Wax, Robert A. (Department: 1653)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
Reexamination Certificate
active
07045505
ABSTRACT:
Isolated nucleic acids molecules, designated 69039 nucleic acid molecules, which encode novel Na+/Ca2+exchanger members, are disclosed. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 69039 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 69039 gene has been introduced or disrupted. Isolated 69039 proteins, fusion proteins, antigenic peptides and anti-69039 antibodies are also disclosed. The invention further provides methods of treating, preventing and diagnosing hematopoietic and neurological disorders.
REFERENCES:
patent: WO 01/09161 (2001-02-01), None
patent: WO 01/83744 (2001-11-01), None
patent: WO 01/837744 (2001-11-01), None
patent: WO 02/33086 (2002-04-01), None
patent: WO 02/046415 (2002-06-01), None
patent: WO 02/059316 (2002-08-01), None
patent: WO 02/081625 (2002-10-01), None
Gabellini, Nadia, “A polymorphic GT repeat from the human cardiac Na+Ca2+exchanger intron 2 activates splicing,” Eur. J. Biochem, 268:1076-1083, 2001.
Kraev, et al., “The Organization of the Human Gene NCX1 Encoding the Sodium-Calcium Exchanger,” Genomics, 37:105-112, 1996.
Kraev, et al., “Homo sapienspartial SCL8A3 gene for solute carrier family 8 (sodium/calcium exchanger), member 3 (SCL8A3), exon 2,” Nov. 12, 2000 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jun. 5, 2005]. Retrieved from the Internet: URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. X93017.
Heilig, et al., “Human chromosome 14 DNA sequence BAC R-486013 of library RPCI-11 from chromosome 14 ofHomo sapiens(Human), complete sequence,” Jul. 10, 2001 (sequence) GenBank [online] Bethesda, MD USA: National Center for Biotechnology Information [retrieved on Jun. 5, 2005]. Retrieved from the Internet: URL: http:www.ncbi
lm.nih.gov/>. GenBank Accession No. AL160191.
Gabellini, N., “Homo sapiensmRNA for sodium/calcium exchanger, SCL8A3, alternative splice form B (SCL8A3 gene),” Jun. 6, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jun. 5, 2005]. Retrieved from the Internet: URL: http:www.ncbi.nlm.nih.gov/>. GenBank Accession No. AJ304853.
Gabellini, N., “Homo sapiensmRNA for sodium/calcium exchanger, SCL8A3, alternative splice form A (SCL8A3 gene),” Jun. 6, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jun. 5, 2005]. Retrieved from the Internet: URL: http:www.ncbi.nlm.nih.gov/>. GenBank Accession No. AJ304852.
Bortoluzzi, S.,Homo sapiensmRNA for Sodium/Calcium Exchanger, SCL8A3, Alternative Splice Form B (SCL8A3 Gene), Jun. 6, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Aug. 7, 2003]. Retrieved from the Internet: URL: http://www.ncbi.nim.nih.gov/>. GenBank Accession No. AJ304853.
Millennium Pharmaceuticals Inc.
Millennium Pharmaceuticals Inc.
Rooke Agnes
Wax Robert A.
LandOfFree
Methods of using 69039, a novel human Na/Ca exchanger family... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of using 69039, a novel human Na/Ca exchanger family..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of using 69039, a novel human Na/Ca exchanger family... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3627952