Method for using thymosin β-10 for gene therapy of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S023100

Reexamination Certificate

active

07037903

ABSTRACT:
A method for using thymosin β-10 for cancer treatment by expressing thymosin β-10 in solid malignant tumor cells. More precisely, the present invention relates to a cancer treatment method wherein thymosin β-10 is expressed in solid malignant tumor cells by infecting adenovirus including thymosin β-10. The gene therapy for cancer using thymosin β-10 of the present invention is very effective for the treatment of ovarian cancer, cervical cancer, stomach cancer and lung cancer.

REFERENCES:
patent: 2002/0168771 (2002-11-01), Gamerman
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A.K. Hall, “Thymosin Beta-10 Accelerates Apoptosis,” Cell and Mol. Bio. Res., 1995, 41(3): 167-180.
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E. Vasile et al., “Differential Expression of Thymosin β-10 by Early Passage and Senescent Vascular Endothelium is Modulated by VPF/VEGF: Evidence for Senescent Endothelial Cells In Vivo at Sites of Atherosclerosis,” The FASEB Jnl., 2001, 15: 458-466.

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