Compounds for the treatment of male erectile dysfunction

Details Compounds for the treatment of male erectile dysfunction Compounds for the treatment of male erectile dysfunction

2006-11-07

2006-11-07

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S312000

Reexamination Certificate

active

07132542

ABSTRACT:
This invention describes compounds of Formula (I) which are modulators of potassium channels and are useful for treating conditions affected by abnormal potassium channel activity including erectile dysfunction and irritable bowel syndrome.

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Boy, Bioorganic & Medicinal Chemistry Letters, vol. 14, pp. 5089-5093, 2004.
P. Hewawasam, et al, “4-Aryl-3-(Hydroxyalkyl)Quinolin-2-Ones: Novel Maxi-K Channel Opening Relaxants of Corporal Smooth Muscle Targeted for Erectile Dysfunction,” J. Med. Chem., 46, pp. 2819-2822, 2003.

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