Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Reexamination Certificate
2006-06-13
2006-06-13
Sheikh, Humera N. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
C424S422000
Reexamination Certificate
active
07060285
ABSTRACT:
The invention provides a dispersion having an oily phase, an aqueous phase, in the form of an oil-in-water emulsion or a water-in-oil emulsion, and at least one active ingredient that is only slightly or with difficulty soluble in the oily phase and the aqueous phase. The dispersion is free from toxicologically dangerous organic solvents. The dispersion contains the active ingredient dissolved in a quantity that is greater than the quantity which results additively from its maximum solubility in the oily and the aqueous phase of the emulsion prior to forming the emulsion.
REFERENCES:
patent: 5534502 (1996-07-01), Seki et al.
patent: 5616330 (1997-04-01), Kaufman et al.
patent: 5651991 (1997-07-01), Sugiyama et al.
patent: 0 296 845 (1988-06-01), None
patent: 0 296 845 (1988-12-01), None
Kan et al., “Development of nonionic surfactant/phospholipid o/w emulsion as a paclitaxel delivery system”,Journal of Controlled Release,58:271-278 (1999).
Manelli Denison & Selter PLLC
Melcher Jeffrey S.
Pharmasol GmbH
Sheikh Humera N.
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