Catalytic antioxidants and methods of use

Details Catalytic antioxidants and methods of use Catalytic antioxidants and methods of use

2006-10-31

2006-10-31

Richter, Johann (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C562S427000, C514S613000, C514S617000, C514S618000, C514S621000

Reexamination Certificate

active

07129374

ABSTRACT:
The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substates for enzymes of the methionine sulfoxide reductase (Msr) class. Some embodiments of the catalytic antioxidant compounds are derived from drugs with anti-inflammatory activity due to inhibition of cyclooxygenase enzymes.

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