Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-12-16
1995-05-30
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549261, 549413, 549477, A01N 4332, C07D30702, C07D30734
Patent
active
054201578
ABSTRACT:
This invention relates to pharmaceutical compounds of structural formulae (I) and (II): ##STR1## and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.
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Bills Gerald F.
Lingham Russell B.
Silverman Keith C.
Singh Sheo B.
Zink Deborah L.
Covington Raymond
Daniel Mark R.
DiPrima Joseph F.
Ivy C. Warren
Merck & Co. , Inc.
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