Methods of treating circadian rhythm disorders

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3140

Patent

active

054201527

ABSTRACT:
A method for treating circadian rhythm disorders is described. The method involves the administration of melatonin from about 6 hours to about 19 hours prior to when the normal sleep phase should begin, depending on whether a phase advance shift in circadian rhythms or a phase delay shift is desired. This is typically from about 4 hours to about 17 hours prior to the time of endogenous melatonin onset.

REFERENCES:
patent: 4600723 (1986-07-01), Short et al.
patent: 4665086 (1987-05-01), Short et al.

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