Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-10-17
2006-10-17
Myers, Carla J. (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023500, C536S024310
Reexamination Certificate
active
07122311
ABSTRACT:
The invention relates to the use of an asthma-associated gene, designated AAGA, the protein molecule encoded by AAGA and related molecules in diagnostic and prognostic screening of patient populations, to polymorphisms in AAGA, and to the use of the protein encoded by AAGA or a variant thereof as a therapeutic target.
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Meyers et al, Genomics, vol. 23, “Evidence for a Locus Regulating Total Serum IgE Levels Mapping to Chronosome 5”, pp. 464-470 (1994).
Postma et al, New England Journal of Medicine, vol. 333, “Genetic Susceptibility to Asthma—Bronchial Hyperresponsiveness coinherited with a major gene for atopy”, pp. 894-900 (1995).
Bleecker et al, Clinical and Experimental Allergy, vol. 25, Supplement 2, “Evidence for linkage of total serum IgE and bronchial hyperresponsiveness to chromosome 5q: a major regulatory locus important in asthma”, pp. 84-88 (1995).
Bleecker Eugene Roland
Meyers Deborah Alexis
Postma Dirkje Sjoukje
Whittaker Paul Andrew
Houghton Gregory C.
Myers Carla J.
Novartis AG
Rijksuniversiteit Groningen
Wake Forest University Health Sciences
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