Vector comprising a replication competent HIV-1 provirus and a h

Chemistry: molecular biology and microbiology – Vector – per se

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4352351, C12N 1586, C12N 1549

Patent

active

060339020

ABSTRACT:
A vector comprising an HIV segment and a heterologous gene segment, which produces a replication competent and an infective HIV virus is disclosed. When the heterologous gene is a marker gene, the spread of the virus can be observed in both in vitro and in vivo systems. The use of this vector in establishing methods for screening anti-viral compounds is also disclosed.

REFERENCES:
Barre-Sinoussi, et al. Science 220:868-871 (1983).
Gallo, et al. Science 224 : 500-503 (1984).
Levy, et al. Science 225:840-842 (1984).
Popovic, et al. Science 224:497-500 (1984).
Sarngadharan et al., Science 224:506-508 (1984).
Siegal; et al. N. Engl. J. Med. 305:1439-1444 (1981).
Zagury, et al. Science 231:850-823 (1986).
Ratner, et al., Nature 313:277-284 (1985).
Sanchez-Pescador, et al., Science 227:484-492 (1985).
Muesing, et al., Nature 313:450-457 (1985).
Wain-Hobson, et al., Cell 40:9-17 (1985).
Sodroski, et al:, Science 231:1549-1553 (1986).
Arya, et al., Science 229:69-73 (1985).
Sodroski, et al., Science 227:171-173 (1985).
Feinberg, et al. Cell 46:807-817 (1986).
Rosen, C.A., et al., Nature 319:555-559 (1986).
Sodroski, et al., Nature 321:412-417 (1986).
Luciw, P.A., et al. PNAS 84:1434-1438 (1987).
Fisher, A.G. et al (1985) Nature 316:262-265.
Kantoff, P.W. et al. (1986) Proc. Natl. Acad. Sci. USA 83:6563-6567.
Mariman, E.C.M. (1985) Nature 318:414.
Tellier, R. et al. (1985) Nature 318:414.
E.F. Terwilliger et al. (1989) Proc. Natl. Acad. Sci. USA 86:3857-3861.
B.R. Cullen et al. (1990) Virology 178:1-5.
S. Wain-Hobson (1989) AIDS 3 (Suppl. 1):513-518.
W. A Haseltine (1988) J. Acquired Imm. Def. Syn. 1:217-240.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Vector comprising a replication competent HIV-1 provirus and a h does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Vector comprising a replication competent HIV-1 provirus and a h, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vector comprising a replication competent HIV-1 provirus and a h will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-361997

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.