Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-09-19
2006-09-19
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S270000
Reexamination Certificate
active
07109235
ABSTRACT:
Laulimalide and epothilone derivatives useful as microtubule stabilizing agents, and in the treatment of cancers are disclosed. Methods of making the compounds and using the compounds as therapeutic agents in treating cancers also are disclosed.
REFERENCES:
patent: 1 295 886 (2003-03-01), None
patent: WO 01/54689 (2001-08-01), None
patent: WO 02/064589 (2002-08-01), None
Mulzer et al. (Angewandte Chemie, International Edition (2001), 40(20), 3842-3846.
D.E. Pryor et al.,Biochemistry, 41, 9109-9115 (2002).
A.K. Ghosh et al.,J. Org. Chem., 66, 8973-8982 (2001).
A.K. Ghosh et al.,J. Am. Chem. Soc., 122, 11027-11028 (2000).
A.K. Ghosh et al.,Tetrahedron Letters, 42, 3399-3401 (2001).
Kifle Bruck
Marshall & Gerstein & Borun LLP
The Board of Trustees of the University Illinois
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